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(3) This potential mechanism and further studies are described below

Transgenic 5xFAD mice have amyloid neuropathology similar to characteristic amyloidplaque pathology in human patients [21, 22], and have been shown to develop impairment in cognitive behaviors that correspond to part of the dementia syndrome in AD

It is located on the central coast of the country, on the shores of the Pacific Ocean, flanked by the coastal desert and extended over the valleys of the Chilln, Rmac and Lurn rivers